Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 7/20 | 0.43 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.40 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749147 | 0.85 | RET (0.53) | RETEIF2AK4OPRK1ACACB | |
| SCHEMBL20474685 | 0.85 | JAK3 (0.44) | ACACB | |
| SCHEMBL30124167 | 0.81 | RET (0.41) | RETEIF2AK4OPRK1OPRM1OPRD1 | |
| SCHEMBL951251 | 0.79 | PDE10A (0.50) | — | |
| SCHEMBL951253 | 0.79 | PDE10A (0.50) | — | |
| SCHEMBL31271961 | 0.79 | PDE10A (0.50) | — | |
| SCHEMBL147265 | 0.78 | DPP4 (0.35) | EIF2AK4ACACB | |
| SCHEMBL147266 | 0.78 | DPP4 (0.35) | EIF2AK4ACACB | |
| SCHEMBL1721356 | 0.78 | DPP4 (0.35) | EIF2AK4ACACB | |
| SCHEMBL25010054 | 0.78 | RET (0.46) | RETEIF2AK4OPRK1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137267-A1 | MODULATORS OF TNF-ALPHA ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |