Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.32 |
| ▸ | SYK | P43405 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.30 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639290 | 1.00 | ALK (0.34) | ALKKCNH2SYKCYP2D6RPS6KB1 | |
| SCHEMBL31639364 | 0.86 | TNF (0.32) | IRAK4 | |
| SCHEMBL31639280 | 0.83 | DNMT3A (0.36) | ALK | |
| SCHEMBL27327565 | 0.83 | FLT3 (0.41) | KCNH2CYP2D6IRAK4CDK2 | |
| SCHEMBL27330136 | 0.83 | FLT3 (0.41) | KCNH2CYP2D6IRAK4CDK2 | |
| SCHEMBL31739699 | 0.77 | FLT3 (0.37) | IRAK4 | |
| SCHEMBL27330147 | 0.77 | FLT3 (0.42) | KCNH2CYP2D6IRAK4 | |
| SCHEMBL27327562 | 0.77 | FLT3 (0.42) | KCNH2CYP2D6IRAK4 | |
| SCHEMBL27329552 | 0.77 | FLT3 (0.37) | IRAK4 | |
| SCHEMBL27326947 | 0.77 | FLT3 (0.37) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |