Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.31 |
| ▸ | NRAS | P01111 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639290 | 0.86 | ALK (0.34) | IRAK4 | |
| SCHEMBL31639283 | 0.86 | ALK (0.34) | IRAK4 | |
| SCHEMBL27330136 | 0.84 | FLT3 (0.41) | CHEK2IRAK4NRASFLT3 | |
| SCHEMBL27327565 | 0.84 | FLT3 (0.41) | CHEK2IRAK4NRASFLT3 | |
| SCHEMBL31639293 | 0.83 | TRPV3 (0.37) | — | |
| SCHEMBL27330374 | 0.81 | FLT3 (0.40) | CHEK1CHEK2IRAK4NRASFLT3 | |
| SCHEMBL27327760 | 0.81 | FLT3 (0.40) | CHEK1CHEK2IRAK4NRASFLT3 | |
| SCHEMBL31639581 | 0.79 | TNF (0.37) | TNF | |
| SCHEMBL27330147 | 0.77 | FLT3 (0.42) | CHEK2IRAK4NRASFLT3 | |
| SCHEMBL27327562 | 0.77 | FLT3 (0.42) | CHEK2IRAK4NRASFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |