Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639104 | 0.91 | HPGD (0.41) | DNMT3APDE4BALDH1A1KDM4EHPGD | |
| SCHEMBL31639293 | 0.90 | TRPV3 (0.37) | DNMT3APDE4BALDH1A1KDM4EHPGD | |
| SCHEMBL31639290 | 0.83 | ALK (0.34) | ALK | |
| SCHEMBL31639283 | 0.83 | ALK (0.34) | ALK | |
| SCHEMBL31639223 | 0.80 | KMT2A (0.43) | DNMT3APDE4BKMT2ATRPV3NSD2 | |
| SCHEMBL31639212 | 0.79 | TRPV3 (0.42) | DNMT3APDE4BALDH1A1KDM4EHPGD | |
| SCHEMBL30698347 | 0.77 | ALK (0.38) | DNMT3APDE4BTRPV3NSD2CCNT1 | |
| SCHEMBL31639276 | 0.74 | NSD2 (0.35) | DNMT3APDE4BALDH1A1KDM4EHPGD | |
| SCHEMBL31000072 | 0.74 | CDK4 (0.45) | DNMT3APDE4BALDH1A1KDM4EHPGD | |
| SCHEMBL31639084 | 0.74 | CDK4 (0.36) | DNMT3AALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |