SCHEMBL3164183

SCHEMBL3164183

C(=Cc1cncc2ccccc12)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
CHAT P28329 3/20 0.45
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
AURKA O14965 1/20 0.44
ERBB2 P04626 1/20 0.44
KDR P35968 1/20 0.44
TRPA1 O75762 1/20 0.42
RELA Q04206 1/20 0.42
NFE2L2 Q16236 1/20 0.42
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
PKM P14618 1/20 0.42
RAB9A P51151 1/20 0.42
SRD5A1 P18405 1/20 0.41
SRD5A2 P31213 1/20 0.41
TRPV1 Q8NER1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3164179 1.00 GRM4 (0.47) GRM4CYP11B1CYP11B2CHATPDGFRB
SCHEMBL3177553 0.85 S100A4 (0.56) GRM4CYP11B1CYP11B2CHATPDGFRB
SCHEMBL3177548 0.85 S100A4 (0.56) GRM4CYP11B1CYP11B2CHATPDGFRB
SCHEMBL7198142 0.81 AURKA (0.44) CYP11B1CYP11B2CHATAURKAERBB2
SCHEMBL3103597 0.81 AURKA (0.44) CYP11B1CYP11B2CHATAURKAERBB2
SCHEMBL3103592 0.81 AURKA (0.44) CYP11B1CYP11B2CHATAURKAERBB2
SCHEMBL3628443 0.79 KMT2A (0.49) AURKAERBB2KDRKDM4ELMNA
SCHEMBL29484670 0.79 KMT2A (0.49) AURKAERBB2KDRKDM4ELMNA
SCHEMBL3628444 0.79 KMT2A (0.49) AURKAERBB2KDRKDM4ELMNA
SCHEMBL6655162 0.78 AURKA (0.45) CYP11B1CYP11B2AURKAERBB2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107063-B1 Photobleachable compounds containing photopolymerizable compositions for use in flexographic printing plates DU PONT (US) 2010-03-10 EP claimed
US-6864039-B2 Such as naphthylvinyl-pyridine; for improved heat stability and image resolution E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-08 US claimed
US-6864039-B2 Such as naphthylvinyl-pyridine; for improved heat stability and image resolution E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-08 US disclosed
US-20030219681-A1 Photobleachable compounds for use in flexographic printing plates CHENG LAP KIN (US) 2003-11-27 US disclosed