SCHEMBL3177553

SCHEMBL3177553

C(=Cc1cncc2ccccc12)c1ccccc1.C(=Cc1nccc2ccccc12)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.56
NQO2 P16083 1/20 0.52
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALK Q9UM73 1/20 0.41
CHAT P28329 2/20 0.40
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
AURKA O14965 1/20 0.39
ERBB2 P04626 1/20 0.39
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3177548 1.00 S100A4 (0.56) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL29578079 0.87 S100A4 (0.69) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL3170396 0.87 S100A4 (0.69) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL3170397 0.87 S100A4 (0.69) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL3164179 0.85 GRM4 (0.47) KDM4ENPC1RAB9ACHATCYP11B1
SCHEMBL3164183 0.85 GRM4 (0.47) KDM4ENPC1RAB9ACHATCYP11B1
SCHEMBL30711554 0.79 S100A4 (0.52) S100A4NQO2KDM4EMEN1NPC1
Heptane SCHEMBL27671681 0.76 S100A4 (0.60) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL28744965 0.75 S100A4 (0.71) S100A4NQO2KDM4EMEN1NPC1
SCHEMBL28744624 0.75 S100A4 (0.67) S100A4NQO2KDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107063-B1 Photobleachable compounds containing photopolymerizable compositions for use in flexographic printing plates DU PONT (US) 2010-03-10 EP disclosed
EP-1107063-A1 Photobleachable compounds containing photopolymerizable compositions for use in flexographic printing plates E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-06-13 EP disclosed