Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31642347 | 0.79 | KCNH2 (0.36) | KCNH2SCN5A | |
| SCHEMBL9496530 | 0.78 | HTT (0.38) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9485950 | 0.76 | MMP2 (0.39) | MMP2MMP3MMP9MMP13 | |
| SCHEMBL31710474 | 0.75 | ALOX5 (0.42) | KCNH2SCN5A | |
| SCHEMBL9377662 | 0.75 | KCNH2 (0.40) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9377308 | 0.74 | MMP2 (0.38) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9377290 | 0.74 | KCNH2 (0.39) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9381481 | 0.72 | KCNH2 (0.40) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL9381651 | 0.71 | KCNH2 (0.39) | KCNH2SCN5AMMP2MMP3MMP9 | |
| SCHEMBL12013041 | 0.70 | BRD4 (0.38) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137537-A1 | COMPOSITIONS AND METHODS FOR TREATING MYC-MEDIATED DISEASES | ARRAKIS THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |