Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286077 | 0.88 | PKM (0.49) | PKMSLC1A2SLC1A1CHRNB2CHRNB4 | |
| SCHEMBL28896076 | 0.86 | NR1H2 (0.48) | PKMNR1H2 | |
| SCHEMBL28499974 | 0.85 | PKM (0.39) | PKM | |
| SCHEMBL30516975 | 0.83 | MAPK1 (0.36) | PKMMAPK1RECQL | |
| SCHEMBL23499281 | 0.83 | MAPK1 (0.36) | PKMMAPK1RECQL | |
| SCHEMBL417787 | 0.81 | L3MBTL1 (0.35) | PKMSLC1A2SLC1A1L3MBTL1PREP | |
| SCHEMBL6016777 | 0.81 | L3MBTL1 (0.38) | PKMSLC1A2SLC1A1L3MBTL1PREP | |
| SCHEMBL2325752 | 0.81 | L3MBTL1 (0.35) | PKMSLC1A2SLC1A1L3MBTL1PREP | |
| SCHEMBL14723681 | 0.81 | L3MBTL1 (0.35) | PKMSLC1A2SLC1A1L3MBTL1PREP | |
| Hydrochloric Acid SCHEMBL10961983 | 0.80 | L3MBTL1 (0.37) | PKML3MBTL1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132542-A1 | MACROCYCLIC OREXIN AGONISTS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-06-26 | — | — | WO | disclosed |