SCHEMBL31647347

SCHEMBL31647347

O=C(COc1ccc2c(c1)OCCO2)N(Cc1cccs1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TRPM8 Q7Z2W7 12/20 0.67
▸ TP53 P04637 5/20 0.58
▸ LMNA P02545 4/20 0.54
▸ THRB P10828 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.53
▸ POLB P06746 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721422 1.00 TRPM8 (0.67) TRPM8TP53LMNATHRBTDP1
SCHEMBL2729280 0.94 TRPM8 (0.70) TRPM8TP53LMNATHRBTDP1
SCHEMBL23126358 0.86 MAOB (0.55) TRPM8LMNAPOLB
SCHEMBL2717391 0.83 TRPM8 (0.84) TRPM8TP53LMNATHRBTDP1
SCHEMBL6408147 0.83 TRPM8 (0.72) TRPM8TP53LMNATHRBTDP1
SCHEMBL2729893 0.82 TRPM8 (0.70) TRPM8TP53LMNATHRBTDP1
SCHEMBL2716916 0.82 TRPM8 (0.78) TRPM8TP53LMNATHRBTDP1
SCHEMBL30582860 0.82 TRPM8 (0.78) TRPM8TP53LMNATHRBTDP1
SCHEMBL2730206 0.81 TRPM8 (0.70) TRPM8TP53LMNATHRBTDP1
SCHEMBL30582854 0.81 TRPM8 (0.70) TRPM8TP53LMNATHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 — — WO disclosed
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