Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647347 | 1.00 | TRPM8 (0.67) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL2729280 | 0.94 | TRPM8 (0.70) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL23126358 | 0.86 | MAOB (0.55) | TRPM8LMNAPOLB | |
| SCHEMBL2717391 | 0.83 | TRPM8 (0.84) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL6408147 | 0.83 | TRPM8 (0.72) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL2729893 | 0.82 | TRPM8 (0.70) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL2716916 | 0.82 | TRPM8 (0.78) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL30582860 | 0.82 | TRPM8 (0.78) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL2730206 | 0.81 | TRPM8 (0.70) | TRPM8TP53LMNATHRBTDP1 | |
| SCHEMBL30582854 | 0.81 | TRPM8 (0.70) | TRPM8TP53LMNATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414048-B | Coated yeast formulation | 弗门尼舍有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-11234450-B2 | Preparations having a cooling effect | SYMRISE AG (DE) | 2022-02-01 | — | — | US | disclosed |
| US-11091734-B2 | Plated yeast formulations | FIRMENICH SA (CH) | 2021-08-17 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3470407-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2019-04-17 | — | — | EP | disclosed |
| US-10182584-B2 | Cooling preparations | SYMRISE AG (DE) | 2019-01-22 | — | — | US | disclosed |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | Seaomyx, Inc. (US) | 2018-07-10 | — | — | US | disclosed |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | Seaomyx, Inc. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20180055069-A1 | PREPARATIONS | SYMRISE AG (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180055069-A1 | PREPARATIONS | SYMRISE AG (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20160317532-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2016-11-03 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885TP53 4485/4885LMNA 4155/4885 |
| US-11234450-B2 | Preparations having a cooling effect | CRAT, CPT2, CPT1A | TRPM8 60/4885TP53 3181/4885LMNA 1034/4885 |
| US-10016418-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885TP53 4485/4885LMNA 4155/4885 |
| US-20160317532-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885TP53 4485/4885LMNA 4155/4885 |
| US-10182584-B2 | Cooling preparations | CRAT, ACAT2, TAS2R50 | TRPM8 62/4885TP53 3036/4885LMNA 1453/4885 |
| US-20180055069-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885TP53 2706/4885LMNA 1435/4885 |
| US-20150313820-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885TP53 2706/4885LMNA 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.