SCHEMBL31648433

SCHEMBL31648433

CCCCCNc1ccc2cc(Br)c(NC(=O)NC(C)(C)C)nc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 19/20 0.45
▸ SRC P12931 6/20 0.41
▸ PDGFRB P09619 3/20 0.41
▸ PDGFRA P16234 3/20 0.41
▸ FGFR2 P21802 7/20 0.41
▸ FGFR4 P22455 7/20 0.41
▸ FGFR3 P22607 7/20 0.41
▸ EGFR P00533 2/20 0.41
▸ PRKD3 O94806 1/20 0.41
▸ PRKCG P05129 1/20 0.41
▸ PRKCB P05771 1/20 0.41
▸ PRKCA P17252 1/20 0.41
▸ PRKCH P24723 1/20 0.41
▸ PRKCI P41743 1/20 0.41
▸ PRKCE Q02156 1/20 0.41
▸ PRKCQ Q04759 1/20 0.41
▸ PRKCZ Q05513 1/20 0.41
▸ PRKCD Q05655 1/20 0.41
▸ PRKD1 Q15139 1/20 0.41
▸ KDR P35968 8/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31647687 0.81 FGFR1 (0.62) FGFR1SRCFGFR2FGFR4FGFR3
SCHEMBL31647777 0.80 FGFR1 (0.60) FGFR1SRCPDGFRBPDGFRAFGFR2
SCHEMBL31647883 0.74 TLR8 (0.43) FGFR1HCAR3
SCHEMBL31648334 0.73 HPGD (0.42) FGFR1KMT2A
SCHEMBL31648010 0.73 RAB9A (0.44) FGFR1GLAHCAR3
SCHEMBL31648385 0.70 FGFR1 (0.61) FGFR1SRCFGFR2FGFR4FGFR3
SCHEMBL31648474 0.70 FGFR1 (0.48) FGFR1SRCFGFR2FGFR4FGFR3
SCHEMBL31647858 0.68 ABL1 (0.34) HCAR3
SCHEMBL31647800 0.66 TLR7 (0.33) —
SCHEMBL16019053 0.65 TLR8 (0.46) HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133660-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
Send feedback