SCHEMBL31648028

SCHEMBL31648028

COc1cc(OC)cc(-c2cc3ccc(NCCCc4ccccc4)nc3nc2NC(=O)NC(C)(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 20/20 0.61
▸ KDR P35968 16/20 0.61
▸ FGFR2 P21802 15/20 0.59
▸ FGFR4 P22455 15/20 0.59
▸ FGFR3 P22607 15/20 0.59
▸ FLT1 P17948 12/20 0.59
▸ FLT4 P35916 12/20 0.59
▸ SRC P12931 2/20 0.54
▸ GLA P06280 1/20 0.54
▸ CSK P41240 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ ATM Q13315 1/20 0.54
▸ EGFR P00533 1/20 0.54
▸ PDGFRB P09619 1/20 0.51
▸ PDGFRA P16234 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31647687 0.88 FGFR1 (0.62) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648385 0.86 FGFR1 (0.61) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648017 0.86 FGFR1 (0.60) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648243 0.84 FGFR1 (0.57) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647773 0.79 PTGDR (0.50) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647768 0.78 FGFR1 (0.51) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648629 0.78 FGFR1 (0.47) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648062 0.78 FGFR1 (0.49) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL24490149 0.77 FGFR1 (0.73) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648166 0.77 FGFR1 (0.67) FGFR1KDRFGFR2FGFR4FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133660-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
Send feedback