SCHEMBL31648136

SCHEMBL31648136

C#CCCCNc1ncc2cc(-c3cc(OC)cc(OC)c3)c([N+](=O)[O-])cc2n1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 16/20 0.44
▸ RPS6KB2 Q9UBS0 1/20 0.44
▸ FGFR1 P11362 19/20 0.43
▸ KDR P35968 17/20 0.43
▸ FGFR2 P21802 15/20 0.43
▸ FGFR3 P22607 15/20 0.43
▸ FLT1 P17948 12/20 0.43
▸ FLT4 P35916 12/20 0.43
▸ GLA P06280 1/20 0.40
▸ SRC P12931 1/20 0.40
▸ CSK P41240 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31647960 0.84 FGFR1 (0.47) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31648124 0.83 FGFR1 (0.39) FGFR4RPS6KB2FGFR1FGFR2FGFR3
SCHEMBL31648077 0.83 FGFR1 (0.43) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31648264 0.80 FGFR1 (0.59) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31647792 0.80 FGFR1 (0.47) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31648508 0.75 PIN1 (0.50) FGFR4RPS6KB2FGFR1FGFR2FGFR3
SCHEMBL15047128 0.73 FGFR1 (0.81) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL15047127 0.70 FGFR1 (0.80) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31648009 0.67 FGFR1 (0.78) FGFR4FGFR1KDRFGFR2FGFR3
SCHEMBL31647959 0.63 FGFR1 (0.46) FGFR4FGFR1KDRFGFR2FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
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