Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.50 |
| ▸ | PPIB | P23284 | 2/20 | 0.46 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | PPIG | Q13427 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194432 | 0.84 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648408 | 0.84 | PPIB (0.48) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648082 | 0.76 | EPHX2 (0.45) | HSP90AA1HSP90AB1HSD11B1MAPTALDH1A1 | |
| SCHEMBL31648163 | 0.76 | PPIB (0.44) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL28511386 | 0.73 | MEN1 (0.55) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648575 | 0.73 | PPIB (0.40) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648466 | 0.73 | PPIB (0.40) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648538 | 0.73 | PPIB (0.40) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL5758265 | 0.72 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648678 | 0.71 | PPIB (0.48) | HSP90AA1HSP90AB1PPIBPPIDPPIG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132946-A1 | PHENYLPYRROLIDINE DERIVATIVES AND THEIR USE AS POI-THETA DERIVATIVES | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |