Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | PPIB | P23284 | 2/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.53 |
| ▸ | PPIG | Q13427 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.50 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758265 | 0.88 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL28511386 | 0.86 | MEN1 (0.55) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL31648898 | 0.84 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL20236634 | 0.80 | HTR1A (0.47) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL30593287 | 0.79 | HTR2C (0.54) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL14698726 | 0.79 | HTR2C (0.54) | HSP90AA1HSP90AB1MEN1KMT2AALDH1A1 | |
| SCHEMBL29643357 | 0.79 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1PPIBPPIDPPIG | |
| SCHEMBL5822054 | 0.76 | GAA (0.49) | MEN1KMT2AGAAHSD11B1 | |
| SCHEMBL938757 | 0.75 | RIPK1 (0.59) | HSP90AA1HSP90AB1SCD5HSD11B1 | |
| SCHEMBL5195419 | 0.75 | HSD17B10 (0.58) | ROCK2SCD5KDM4EHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773796-A2 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006021655-A2 | OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-03-02 | — | — | WO | disclosed |