Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.59 |
| ▸ | NLN | Q9BYT8 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | ARG1 | P05089 | 2/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | TRHR | P34981 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 2/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649400 | 0.85 | DPP4 (0.53) | DPP4DPP7NLNTRHRREN | |
| SCHEMBL26625862 | 0.84 | DPP4 (0.71) | DPP4DPP7NLNCYP3A4SLC7A5 | |
| SCHEMBL27210419 | 0.84 | DPP4 (0.71) | DPP4DPP7NLNCYP3A4SLC7A5 | |
| SCHEMBL30477930 | 0.84 | DPP4 (0.71) | DPP4DPP7NLNCYP3A4SLC7A5 | |
| SCHEMBL27484466 | 0.83 | DPP4 (0.69) | DPP4DPP7NLNCYP3A4SLC7A5 | |
| SCHEMBL30839655 | 0.80 | DPP4 (0.66) | DPP4DPP7NLNCYP3A4SLC7A5 | |
| SCHEMBL31649050 | 0.74 | DPP7 (0.60) | DPP4DPP7 | |
| SCHEMBL22300350 | 0.73 | DPP4 (0.56) | DPP4DPP7NLNTRHRREN | |
| Histidine SCHEMBL5491751 | 0.72 | CYP3A4 (0.74) | DPP4DPP7CYP3A4SLC7A5PPM1B | |
| SCHEMBL27776880 | 0.72 | CYP3A4 (0.57) | DPP4NLNCYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |