SCHEMBL26625862

SCHEMBL26625862

N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.71
▸ DPP7 Q9UHL4 1/20 0.62
▸ CYP3A4 P08684 1/20 0.54
▸ SLC7A5 Q01650 1/20 0.54
▸ NLN Q9BYT8 3/20 0.53
▸ TRHR P34981 1/20 0.52
▸ ARG1 P05089 2/20 0.47
▸ ARG2 P78540 1/20 0.47
▸ REN P00797 3/20 0.46
▸ BTK Q06187 2/20 0.44
▸ HRH2 P25021 1/20 0.44
▸ HRH1 P35367 1/20 0.44
▸ ACE P12821 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30477930 1.00 DPP4 (0.71) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL27210419 1.00 DPP4 (0.71) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL30839655 0.87 DPP4 (0.66) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL27273680 0.86 DPP4 (0.56) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL31649037 0.84 DPP4 (0.71) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL27484466 0.83 DPP4 (0.69) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL22300350 0.80 DPP4 (0.56) DPP4DPP7NLNTRHRREN
SCHEMBL27726234 0.77 NLN (0.64) DPP4DPP7CYP3A4SLC7A5NLN
SCHEMBL27210409 0.77 TRHR (0.54) DPP4TRHRRENACE
SCHEMBL5734357 0.77 DPP4 (0.44) DPP4DPP7RENHRH1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619020-A1 COMPOSITION AND METHOD FOR PROLONG SURVIVAL OF TRANSPLANT AND RECIPIENT NovMetaPharma Co., Ltd. (KR) 2025-09-24 — — EP claimed
US-20240197816-A1 COMPOSITION AND METHOD FOR PROLONG SURVIVAL OF TRANSPLANT AND RECIPIENT NOVMETAPHARMA CO., LTD. (KR) 2024-06-20 — — US claimed
CN-117677302-A Peptide compounds for flavor modulation CJ第一制糖株式会社 2024-03-08 — — CN claimed
CN-114380695-B Novel method for simply and rapidly realizing C-C bond formation reaction 吉林大学 2024-02-13 — — CN claimed
CN-85105655-A Process for preparing novel derivatives of 1-methyl-4, 5-dihydroorotic acid and pharmaceutical compositions thereof — 1987-01-28 — — CN claimed
WO-2025230339-A1 USE OF CYCLO-HISPRO ALONE OR ZINC AND CYCLO-HISPRO FOR INHIBITING MUSCLE LOSS OR ALLEVIATING MUSCLE FUNCTION DECLINE CAUSED BY ANTI-OBESITY DRUGS 주식회사 노브메타파마 2025-11-06 — — WO disclosed
WO-2025230339-A1 USE OF CYCLO-HISPRO ALONE OR ZINC AND CYCLO-HISPRO FOR INHIBITING MUSCLE LOSS OR ALLEVIATING MUSCLE FUNCTION DECLINE CAUSED BY ANTI-OBESITY DRUGS 주식회사 노브메타파마 2025-11-06 — — WO disclosed
EP-4619020-A1 COMPOSITION AND METHOD FOR PROLONG SURVIVAL OF TRANSPLANT AND RECIPIENT NovMetaPharma Co., Ltd. (KR) 2025-09-24 — — EP disclosed
CN-120112534-A PEG modified cyclic dipeptides 诺麦塔制药有限公司 2025-06-06 — — CN disclosed
CN-119925563-A Small molecule peptide composition for repairing cerebral apoplexy brain cells based on stem cell targeting 北京钦川科技有限公司 2025-05-06 — — CN disclosed
CN-119798264-A Application of cyclo (-HIS-PRO) hydrate 诺麦塔制药有限公司 2025-04-11 — — CN disclosed
CN-119798264-A Application of cyclo (-HIS-PRO) hydrate 诺麦塔制药有限公司 2025-04-11 — — CN disclosed
CN-115666543-A Coronavirus therapeutic agents and methods of treatment 血管免疫治疗公司 2023-01-31 — — CN disclosed
EP-4122484-A1 USE OF CYCLO-HISPRO (CHP) FOR LOWERING BLOOD PRESSURE Novmetapharma Co., Ltd. (KR) 2023-01-25 — — EP disclosed
US-11524979-B2 Macrocyclic polypeptides UNIVERSITY OF WASHINGTON (US) 2022-12-13 — — US disclosed
EP-3967321-A1 USE OF CYCLO-HIS-PRO (CHP) FOR PREVENTING, AMELIORATING, OR TREATING FIBROSIS Novmetapharma Co., Ltd. (KR) 2022-03-16 — — EP disclosed
EP-3383423-B1 POLYPEPTIDES AND ANALOGUES THEREOF FOR USE IN THE TREATMENT OF DIABETES AND BONE DISORDERS UNIV ULSTER (GB) 2022-03-09 — — EP disclosed
EP-3949976-A1 USE OF CYCLO HIS-PRO (CHP) FOR PREVENTING, ALLEVIATING OR TREATING PERITONEAL FIBROSIS Novmetapharma Co., Ltd. (KR) 2022-02-09 — — EP disclosed
CN-101951935-A Therapeutic agent for cerebral ischemic disorder OTSUKA PHARMA CO LTD 2011-01-19 — — CN disclosed
CN-101309682-A Modulation of neurogenesis by pde inhibition BRAINCELLS INC (US) 2008-11-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197816-A1 COMPOSITION AND METHOD FOR PROLONG SURVIVAL OF TRANSPLANT AND RECIPIENT CHP1, CETP, PCTP DPP4 2308/4885DPP7 2208/4885CYP3A4 2113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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