Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.47 |
| ▸ | DPP4 | P27487 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.42 |
| ▸ | FAP | Q12884 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649183 | 0.88 | DPP7 (0.51) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31649315 | 0.85 | DPP4 (0.52) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31649106 | 0.85 | HTR1A (0.52) | DPP7DPP4SMN1; SMN2DPP8DPP9 | |
| SCHEMBL770503 | 0.79 | HSD17B10 (0.56) | DPP4NPC1RAB9ASMN1; SMN2DPP8 | |
| SCHEMBL770733 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2HTR1AHTR7HRH1DRD3 | |
| SCHEMBL31649265 | 0.76 | ACE (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649395 | 0.76 | DRD2 (0.45) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649050 | 0.75 | DPP7 (0.60) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL770858 | 0.75 | ACHE (0.60) | SMN1; SMN2HTR1AHTR7HRH1DRD3 | |
| SCHEMBL15377479 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2HTR1AHTR7HRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |