Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | CPS1 | P31327 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649235 | 0.92 | HTR2A (0.41) | HTR2ARORCCPS1ADRB2ALDH1A1 | |
| SCHEMBL31649406 | 0.90 | KMT2A (0.40) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649053 | 0.90 | KMT2A (0.40) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649051 | 0.90 | HTR2A (0.40) | HTR2ARORCCPS1ADRB2ALDH1A1 | |
| SCHEMBL31649296 | 0.85 | HTR2A (0.40) | HTR2ARORCALDH1A1MEN1KMT2A | |
| SCHEMBL31649363 | 0.85 | HTR2A (0.37) | HTR2ARORCADRB2ALDH1A1MEN1 | |
| SCHEMBL31648994 | 0.85 | TSHR (0.40) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649351 | 0.84 | TSHR (0.39) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649369 | 0.83 | TSHR (0.39) | ALDH1A1MEN1KMT2APOLBHTT | |
| SCHEMBL31649412 | 0.82 | KMT2A (0.43) | ALDH1A1MEN1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |