Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | CPS1 | P31327 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649260 | 0.92 | HTR2A (0.41) | HTR2ACPS1MEN1KMT2ARORC | |
| SCHEMBL31649051 | 0.91 | HTR2A (0.40) | HTR2ACPS1MEN1KMT2ARORC | |
| SCHEMBL31649412 | 0.90 | KMT2A (0.43) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL31649370 | 0.90 | KMT2A (0.43) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL31649363 | 0.86 | HTR2A (0.37) | HTR2AMEN1KMT2ARORCADRB2 | |
| SCHEMBL31649296 | 0.86 | HTR2A (0.40) | HTR2AMEN1KMT2ARORCALDH1A1 | |
| SCHEMBL31649339 | 0.85 | DPP4 (0.42) | HTR2AALDH1A1OPRM1 | |
| SCHEMBL31649062 | 0.85 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL31649393 | 0.83 | TSHR (0.41) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL31649406 | 0.82 | KMT2A (0.40) | MEN1KMT2AALDH1A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | claimed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |