Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649158 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL31649185 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL31649206 | 0.91 | OPRM1 (0.39) | HTR2AALDH1A1KDM4ESIGMAR1RORC | |
| SCHEMBL31649151 | 0.89 | ACHE (0.43) | SIGMAR1KCNA5HSD11B1CCR5 | |
| SCHEMBL31649462 | 0.89 | ACHE (0.43) | SIGMAR1KCNA5HSD11B1CCR5 | |
| SCHEMBL31649235 | 0.86 | HTR2A (0.41) | HTR2AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31649260 | 0.85 | HTR2A (0.41) | HTR2AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31649051 | 0.84 | HTR2A (0.40) | HTR2AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL31649113 | 0.84 | TACR1 (0.39) | HTR2AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31649065 | 0.83 | TACR1 (0.39) | ALDH1A1MEN1KMT2AKDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |