Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649331 | 0.93 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649328 | 0.83 | TACR1 (0.42) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL31649370 | 0.83 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649412 | 0.83 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649406 | 0.82 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649053 | 0.82 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649393 | 0.81 | TSHR (0.41) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649325 | 0.81 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649223 | 0.81 | SLC6A2 (0.40) | KMT2AMEN1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL31649455 | 0.81 | KMT2A (0.41) | KMT2AMEN1ALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |