Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649187 | 0.93 | TACR1 (0.41) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649340 | 0.93 | TACR1 (0.41) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649306 | 0.83 | KMT2A (0.38) | TACR1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL31649410 | 0.80 | KMT2A (0.45) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649178 | 0.80 | KMT2A (0.45) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649427 | 0.79 | ALDH1A1 (0.46) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649428 | 0.79 | KMT2A (0.45) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649329 | 0.79 | KMT2A (0.41) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649366 | 0.79 | F2 (0.45) | TACR1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL31649055 | 0.78 | ACE (0.46) | KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |