Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799905 | 0.92 | GNPAT (0.67) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL17732678 | 0.92 | GNPAT (0.67) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL7437335 | 0.92 | GNPAT (0.63) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL30533197 | 0.92 | GNPAT (0.67) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL25626304 | 0.88 | ACE (0.60) | GNPATMMECTSSCTSKACE | |
| SCHEMBL30799536 | 0.87 | LTA4H (0.64) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL17192787 | 0.86 | GNPAT (0.64) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL1081111 | 0.86 | GNPAT (0.73) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL6677690 | 0.86 | GNPAT (0.73) | GNPATMMECTSSCTSKPAM | |
| SCHEMBL5692056 | 0.86 | GNPAT (0.73) | GNPATMMECTSSCTSKPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3628046-B1 | SUBTILISIN VARIANTS HAVING A MUTATION IN THE S2 OR S2' POCKET | FRESENIUS KABI IPSUM S R L (IT) | 2025-07-02 | — | — | EP | disclosed |