SCHEMBL3165155

SCHEMBL3165155

O=S(=O)(Cl)/C=C/c1ccc(Cl)s1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.45
PTGS2 P35354 1/20 0.45
F10 P00742 15/20 0.38
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
F2 P00734 1/20 0.34
KLKB1 P03952 1/20 0.34
PSMD14 O00487 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3165162 1.00 PTGS1 (0.45) PTGS1PTGS2F10MAOAMAOB
SCHEMBL4627759 0.82 PTGS1 (0.47) PTGS1PTGS2F10MAOAMAOB
SCHEMBL686180 0.82 PTGS1 (0.44) PTGS1PTGS2F10MAOAMAOB
SCHEMBL4627757 0.82 PTGS1 (0.47) PTGS1PTGS2F10MAOAMAOB
SCHEMBL5646039 0.78 PTGS1 (0.46) PTGS1PTGS2F10MEN1KMT2A
SCHEMBL5646036 0.78 PTGS1 (0.46) PTGS1PTGS2F10MEN1KMT2A
SCHEMBL4939340 0.78 MEN1 (0.37) F10MEN1KMT2A
SCHEMBL4939345 0.78 MEN1 (0.37) F10MEN1KMT2A
SCHEMBL13991504 0.78 PTGS1 (0.44) PTGS1PTGS2F10F2KLKB1
SCHEMBL4061257 0.75 PTGS1 (0.43) PTGS1PTGS2MAOAMAOBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115874239-B Electroplating process 温州市金牛电镀有限公司 2025-04-08 CN claimed
CN-115874239-A Electroplating process 温州市金牛电镀有限公司 2023-03-31 CN claimed
CN-115874239-B Electroplating process 温州市金牛电镀有限公司 2025-04-08 CN disclosed
CN-115874239-A Electroplating process 温州市金牛电镀有限公司 2023-03-31 CN disclosed
US-7645338-B2 Crystalline derivatives of (E)-2-(5-chlorothien-2-yl)-N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}ethenesulfonamide GLAXO GROUP LIMITED (GB) 2010-01-12 US disclosed
US-7612075-B2 Substituted oxoazaheterocyclyl compounds AVENTIS PHARMACEUTICALS INC. (US) 2009-11-03 US disclosed
US-20090170844-A1 Spiro Tetracyclic Compound MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2009-07-02 US disclosed
US-20090099231-A1 3-Sulfonylamino-Pyrrolidine-2-One Derivatives as Factor Xa Inhibitors GLAXO GROUP LIMITED (GB) 2009-04-16 US disclosed
US-7517879-B2 Pyrrolidine derivatives as factor Xa inhibitors GLAXO GROUP LIMITED (GB) 2009-04-14 US disclosed
EP-2020411-A1 SPIRO TETRACYCLIC COMPOUND MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2009-02-04 EP disclosed
US-7482374-B2 Pyrrolidine-2-ones as Factor Xa inhibitors GLAXO GROUP LIMITED (GB) 2009-01-27 US disclosed
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds AVENTIS PHARMACEUTICALS PRODUCTS INC. 2002-01-31 US disclosed
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
US-6281227-B1 INHIBITORS OF THE ACTIVITY OF FACTOR XA. AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-28 US disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO disclosed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP disclosed
WO-2000032590-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 2000-06-08 WO disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170844-A1 Spiro Tetracyclic Compound KCNH1, TFPI, KCNN2 PTGS1 1736/4885PTGS2 2140/4885F10 127/4885
US-20090099231-A1 3-Sulfonylamino-Pyrrolidine-2-One Derivatives as Factor Xa Inhibitors TFPI, SERPINC1, SERPINE1 PTGS1 741/4885PTGS2 1284/4885F10 11/4885
US-20020013310-A1 Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds STS, ARSA, F12 PTGS1 695/4885PTGS2 1077/4885F10 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.