Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.47 |
| ▸ | SKP1 | P63208 | 1/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269830 | 0.82 | GPR119 (0.48) | POLBGPR119CKS1BSKP1SKP2 | |
| SCHEMBL10317314 | 0.82 | POLB (0.58) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL22391780 | 0.82 | POLB (0.58) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL3538823 | 0.82 | KDM4E (0.59) | POLBGPR119MAPTALDH1A1 | |
| SCHEMBL30592004 | 0.81 | POLB (0.57) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL21401570 | 0.81 | POLB (0.57) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL123592 | 0.81 | POLB (0.71) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL14206364 | 0.81 | POLB (0.57) | POLBGPR119SMARCA2SMARCA4PBRM1 | |
| SCHEMBL652792 | 0.81 | GRM5 (0.53) | GPR119SMARCA2SMARCA4PBRM1CKS1B | |
| SCHEMBL16040669 | 0.81 | GPR119 (0.52) | GPR119SMARCA2SMARCA4PBRM1CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214977-A1 | STAT6 INHIBITORS AND USES THEREOF | STAT6, STAT5B, STAT5A | POLB 4132/4885GPR119 770/4885SMARCA2 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.