SCHEMBL316600

SCHEMBL316600

C=Cc1ccc(COCCCCOCc2ccc(C=C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TEAD3 Q99594 2/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
TSHR P16473 2/20 0.36
NAAA Q02083 2/20 0.36
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
UGCG Q16739 5/20 0.33
GBA2 Q9HCG7 5/20 0.33
GBA1 P04062 4/20 0.33
LCT P09848 2/20 0.33
SI P14410 2/20 0.33
MGAM O43451 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18868387 0.98 ALDH1A1 (0.44) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL316695 0.96 ALDH1A1 (0.46) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL18832287 0.91 ALDH1A1 (0.50) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL4903352 0.91 ALDH1A1 (0.38) ALDH1A1TDP1L3MBTL1TEAD3UGCG
SCHEMBL1664388 0.91 CA1 (0.40) ALDH1A1TDP1L3MBTL1CHRNB2CHRNB4
SCHEMBL10071502 0.91 TDP1 (0.42) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL8773211 0.91 TDP1 (0.39) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL27090353 0.91 ALDH1A1 (0.38) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL14076881 0.91 ALDH1A1 (0.38) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2
SCHEMBL28299477 0.91 ALDH1A1 (0.38) ALDH1A1TDP1L3MBTL1TEAD3CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-11814450-B2 Polymeric solid support for oligonucleotide synthesis HONGENE BIOTECH CORPORATION (US) 2023-11-14 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed
US-20230130509-A1 POLYMERIC SOLID SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS HONGENE BIOTECH CORPORATION 2023-04-27 US disclosed
US-20200181317-A1 Bisphenol A-Free Crosslinked Polymer Composition WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2020-06-11 US disclosed
US-8092720-B2 Polymer-supported metal complex catalyst NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2012-01-10 US disclosed
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227743-A1 POLYMER-SUPPORTED METAL COMPLEX CATALYST PYM1, ARG1, SCO2 ALDH1A1 2736/4885TDP1 4228/4885L3MBTL1 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.