Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | QDPR | P09417 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661181 | 0.77 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL31661169 | 0.77 | MAPKAPK2 (0.38) | DDB1CRBNMAPKAPK2HTR6DRD3 | |
| SCHEMBL31661205 | 0.70 | QDPR (0.38) | QDPRHTR6HTR2CSLC18A3SIGMAR1 | |
| SCHEMBL31661222 | 0.68 | HTR3E (0.34) | DRD3 | |
| SCHEMBL24881330 | 0.66 | HTR2C (0.42) | DDB1CRBNQDPRHTR2CSLC18A3 | |
| SCHEMBL27039554 | 0.66 | CRBN (0.41) | DDB1CRBNQDPRHTR2CSLC18A3 | |
| SCHEMBL29197784 | 0.66 | DDB1 (0.41) | DDB1CRBNQDPRHTR2CSLC18A3 | |
| SCHEMBL27073454 | 0.66 | HTR2C (0.42) | DDB1CRBNQDPRHTR2CSLC18A3 | |
| SCHEMBL23411561 | 0.66 | EPHX2 (0.64) | EPHX2QDPRHTR6 | |
| SCHEMBL5584682 | 0.66 | QDPR (0.47) | QDPRHTR6DRD3HTR2CSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |