Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661243 | 0.80 | SMN1; SMN2 (0.35) | KMT2ACYP1A2MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31661252 | 0.68 | KDM4E (0.35) | KDM4E | |
| SCHEMBL8315301 | 0.67 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL196599 | 0.67 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7975453 | 0.66 | KMT2A (0.59) | KMT2ACYP1A2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6112657 | 0.66 | KMT2A (0.64) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1684499 | 0.66 | KDM4E (0.67) | KMT2ACYP1A2PKMALDH1A1MAPT | |
| SCHEMBL23335815 | 0.66 | KDM4E (0.46) | CYP1A2ALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL13197089 | 0.64 | KMT2A (0.46) | KMT2ACYP1A2MEN1PKMMDM2 | |
| SCHEMBL7978700 | 0.64 | KMT2A (0.60) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |