Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661355 | 0.78 | — | — | |
| SCHEMBL31661363 | 0.78 | KDM4E (0.43) | KDM4E | |
| SCHEMBL31661229 | 0.77 | — | — | |
| SCHEMBL31661272 | 0.68 | KMT2A (0.50) | KDM4E | |
| SCHEMBL3549382 | 0.64 | NPC1 (0.59) | BRD4BRD2BRD3BAZ2BBAZ2A | |
| SCHEMBL24247829 | 0.62 | NPC1 (0.63) | KDM4EBAZ2BBAZ2A | |
| SCHEMBL20986101 | 0.61 | NPC1 (0.45) | KDM4EBRD4BRD2BRD3BAZ2B | |
| SCHEMBL20986031 | 0.61 | NPC1 (0.45) | KDM4EBRD4BRD2BRD3BAZ2B | |
| SCHEMBL23889085 | 0.60 | USP30 (0.44) | KDM4EBAZ2BBAZ2A | |
| SCHEMBL1204351 | 0.59 | ALDH1A1 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |