Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.68 |
| ▸ | GABRD | O14764 | 2/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.68 |
| ▸ | GABRE | P78334 | 2/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.68 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.68 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.68 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.68 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 4/20 | 0.48 |
| ▸ | NOS2 | P35228 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1159738 | 1.00 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL6227701 | 0.98 | GABRP (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL220538 | 0.81 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30705741 | 0.81 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL446809 | 0.81 | GABRP (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL22797869 | 0.79 | GABRP (0.96) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19586492 | 0.79 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16604296 | 0.79 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL339851 | 0.79 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10819643 | 0.79 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |