Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.68 |
| ▸ | GABRD | O14764 | 3/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.68 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.68 |
| ▸ | GABRE | P78334 | 3/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.68 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.68 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.68 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.68 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 4/20 | 0.43 |
| ▸ | NOS2 | P35228 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220538 | 0.81 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30705741 | 0.81 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL446809 | 0.81 | GABRP (0.70) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31661275 | 0.79 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL22797869 | 0.79 | GABRP (0.96) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1159738 | 0.79 | GABRP (0.68) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3194722 | 0.78 | KDM5C (0.53) | KDM4EKDM5CKDM5BKDM6BKDM4A | |
| Hydrochloric Acid SCHEMBL6227701 | 0.78 | GABRP (0.66) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL73194 | 0.77 | TAS1R3 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30182299 | 0.77 | ALDH1A1 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127903-A1 | SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| US-12048747-B2 | Substituted piperidine Degronimers for Target Protein degradation | C4 THERAPEUTICS, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-20220313827-A1 | SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2022-10-06 | — | — | US | disclosed |
| EP-3455219-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127903-A1 | SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | STUB1, UBE3C, NEDD4 | GABRP 816/4885GABRD 192/4885GABRA1 459/4885 |
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | GCGR, STUB1, GID4 | GABRP 1877/4885GABRD 878/4885GABRA1 926/4885 |
| US-20220313827-A1 | SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | STUB1, UBE3C, NEDD4 | GABRP 816/4885GABRD 192/4885GABRA1 459/4885 |
| US-12048747-B2 | Substituted piperidine Degronimers for Target Protein degradation | GID4, RNF5, UBE3C | GABRP 1008/4885GABRD 245/4885GABRA1 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.