Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.75 |
| ▸ | NPC1 | O15118 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7069217 | 0.85 | KMT2A (0.79) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL16295141 | 0.84 | MAPT (0.69) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL26854287 | 0.83 | RAB9A (0.66) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL31398683 | 0.80 | NPC1 (0.61) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL2682648 | 0.80 | RAB9A (1.00) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL558304 | 0.78 | NPC1 (0.62) | RAB9ANPC1ALDH1A1NPSR1LMNA | |
| SCHEMBL16670942 | 0.78 | RAB9A (0.77) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL19329247 | 0.76 | EPHX1 (0.63) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL2871030 | 0.76 | SMN1; SMN2 (0.57) | RAB9ANPC1KMT2AALDH1A1MEN1 | |
| SCHEMBL2832098 | 0.76 | NPC1 (0.72) | RAB9ANPC1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |