SCHEMBL7069217

SCHEMBL7069217

O=C(Nc1ccc(Cl)cn1)c1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.79
MEN1 O00255 3/20 0.79
RAB9A P51151 6/20 0.78
NPC1 O15118 5/20 0.78
CASP3 P42574 1/20 0.76
SENP8 Q96LD8 1/20 0.76
SENP7 Q9BQF6 1/20 0.76
SENP6 Q9GZR1 1/20 0.76
SMN1; SMN2 Q16637 4/20 0.73
TSHR P16473 2/20 0.72
TP53 P04637 1/20 0.72
NFKB1 P19838 1/20 0.72
NFKB2 Q00653 1/20 0.72
RELA Q04206 1/20 0.72
ALDH1A1 P00352 1/20 0.69
PKM P14618 1/20 0.69
HCAR3 P49019 1/20 0.69
HTT P42858 2/20 0.64
ALOX15 P16050 1/20 0.64
TDP1 Q9NUW8 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3165548 0.86 RAB9A (0.77) KMT2AMEN1RAB9ANPC1SMN1; SMN2
SCHEMBL31661287 0.85 RAB9A (0.75) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL11887841 0.84 SMN1; SMN2 (1.00) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL6714901 0.84 RAB9A (0.61) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL29858775 0.84 RAB9A (0.73) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL20435596 0.84 RAB9A (0.73) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL3409610 0.84 RAB9A (0.73) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL11268411 0.83 NPC1 (0.72) KMT2AMEN1RAB9ANPC1CASP3
SCHEMBL13315095 0.83 F10 (0.73) KMT2AMEN1RAB9ANPC1SMN1; SMN2
SCHEMBL3164310 0.82 RAB9A (1.00) KMT2AMEN1RAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12269814-B2 Process for preparing a compound useful to treat mycoses PULMOCIDE LIMITED (GB) 2025-04-08 US disclosed
US-11661415-B2 Process for preparing a compound useful to treat mycoses PULMOCIDE LIMITED (GB) 2023-05-30 US disclosed
WO-2023061440-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-04-20 WO disclosed
EP-4157888-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS Cullgen (Shanghai), Inc. (CN) 2023-04-05 EP disclosed
WO-2021239117-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2021-12-02 WO disclosed
EP-3362436-B1 PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS UNIV ANTWERPEN (BE) 2021-06-30 EP disclosed
WO-2003048081-A2 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO disclosed
EP-1140903-A1 AROMATIC AMIDES ELI LILLY AND COMPANY (US) 2001-10-10 EP disclosed
WO-2000039118-A1 AROMATIC AMIDES ELI LILLY AND COMPANY (US) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661415-B2 Process for preparing a compound useful to treat mycoses DPM1, CYP51A1, ERG28 KMT2A 2920/4885MEN1 142/4885RAB9A 1450/4885
US-12269814-B2 Process for preparing a compound useful to treat mycoses C1R, CBR1, CBR3 KMT2A 2663/4885MEN1 146/4885RAB9A 1340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.