Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405765 | 0.83 | NOTUM (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL17144343 | 0.83 | NOTUM (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL18725355 | 0.81 | SMN1; SMN2 (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL2417340 | 0.81 | CYP1A2 (0.59) | NOTUMCYP1A2NPC1RAB9AMAPT | |
| SCHEMBL15972630 | 0.80 | MAPT (0.45) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL16652958 | 0.80 | GRM4 (0.51) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL30342124 | 0.80 | MAPT (0.45) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL31306903 | 0.79 | MAPK1 (0.50) | MAPK1CYP1A2NPC1RAB9ATP53 | |
| SCHEMBL908091 | 0.79 | MAPK1 (0.50) | MAPK1CYP1A2NPC1RAB9ATP53 | |
| SCHEMBL18498646 | 0.79 | KDM4E (0.44) | NOTUMMAPK1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |