Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405765 | 1.00 | NOTUM (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL2255434 | 0.83 | SMN1; SMN2 (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL16372354 | 0.83 | LCK (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL31500498 | 0.83 | SMN1; SMN2 (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL31661385 | 0.83 | NOTUM (0.45) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL1615811 | 0.83 | NPC1 (0.46) | MAPK1CYP1A2NPC1RAB9ATP53 | |
| SCHEMBL18725355 | 0.83 | SMN1; SMN2 (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL30093142 | 0.83 | LCK (0.46) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL2593348 | 0.81 | PTPN1 (0.50) | NOTUMMAPK1CYP1A2NPC1RAB9A | |
| SCHEMBL7236303 | 0.81 | CTSA (0.48) | NOTUMMAPK1CYP1A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615573-A1 | GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2025-09-17 | — | — | EP | disclosed |
| US-20250092033-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Avistone Biotechnology Co., Ltd. (CN) | 2025-03-20 | — | — | US | disclosed |
| US-20240368122-A1 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS INC (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4458818-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Beijing Avistone Biotechnology Co., Ltd. (CN) | 2024-11-06 | — | — | EP | disclosed |
| EP-4387964-A1 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024102625-A1 | GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20240083908-A1 | TETRAHYDROTHIENOPYRIMIDINESULFONAMIDE COMPOUNDS | ALIVEXIS, INC. (JP) | 2024-03-14 | — | — | US | disclosed |
| CN-116003406-B | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| EP-4269415-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | Modulus Discovery, Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| CN-116583286-A | Tetrahydrothienopyrimidine sulfonamide compounds | 某久拉斯株式会社 | 2023-08-11 | — | — | CN | disclosed |
| US-20160376262-A1 | NOVEL PYRIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2016-12-29 | — | — | US | disclosed |
| WO-2016191245-A1 | RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING | DOW AGROSCIENCES LLC (US) | 2016-12-01 | — | — | WO | disclosed |
| US-20160340311-A1 | RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING | DOW AGROSCIENCES LLC (US) | 2016-11-24 | — | — | US | disclosed |
| CN-106132958-A | Pyridine 2 amides compound as CB2 agonist | 豪夫迈·罗氏有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105377830-A | 4-amino-6-(heterocyclic)picolinates and 6-amino-2-(heterocyclic) pyrimidine-4-carboxylates and their use as herbicides | DOW AGROSCIENCES LLC | 2016-03-02 | — | — | CN | disclosed |
| CN-105209451-A | 4-amino-6- (heterocyclyl) pyridine-2-carboxylic acid esters and 6-amino-2-2 (heterocyclyl) pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |
| CN-105209452-A | 4-amino-6- (heterocyclyl) pyridine-2-carboxylic acid esters and 6-amino-2- (heterocyclyl) pyrimidine-4-carboxylic acid esters and their use as herbicides | DOW AGROSCIENCES LLC | 2015-12-30 | — | — | CN | disclosed |
| WO-2015150440-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-10-08 | — | — | WO | disclosed |
| CN-1245401-C | 6-aryl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-03-15 | — | — | CN | disclosed |
| CN-1551876-A | 6-aryl-4-aminopicolinates and their use as herbicides | �ݶ�ũ������˾ | 2004-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083908-A1 | TETRAHYDROTHIENOPYRIMIDINESULFONAMIDE COMPOUNDS | TYMS, TYMP, TPMT | NOTUM 1116/4885MAPK1 1982/4885CYP1A2 1688/4885 |
| US-20240368122-A1 | JAK2 INHIBITORS AND METHODS OF USE THEREOF | JAK2, JAK1, JAK3 | NOTUM 2441/4885MAPK1 590/4885CYP1A2 3921/4885 |
| US-20250092033-A1 | HETEROAROMATIC NITROGEN-OXIDE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | CYP19A1, WEE1, WEE2 | NOTUM 53/4885MAPK1 3546/4885CYP1A2 130/4885 |
| US-20160340311-A1 | RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING | DDT, PARK7, DDO | NOTUM 1623/4885MAPK1 4248/4885CYP1A2 2325/4885 |
| US-20160376262-A1 | NOVEL PYRIDINE DERIVATIVES | NDUFS6, NDUFS4, NDUFV1 | NOTUM 3969/4885MAPK1 747/4885CYP1A2 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.