Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079553 | 1.00 | NPC1 (0.48) | NPC1HSP90AA1SLC6A2SLC29A1PAX8 | |
| SCHEMBL915161 | 0.90 | HTR6 (0.46) | SLC29A1PAX8SMN1; SMN2MAPTKDM4E | |
| SCHEMBL7079675 | 0.85 | SLC6A2 (0.57) | NPC1HSP90AA1SLC6A2SLC29A1PAX8 | |
| SCHEMBL2263749 | 0.84 | NPC1 (0.64) | NPC1HSP90AA1PAX8PLGPLAU | |
| SCHEMBL29263648 | 0.81 | SLC6A2 (0.47) | NPC1HSP90AA1SLC6A2PLGPLAU | |
| SCHEMBL31035977 | 0.81 | SLC6A2 (0.47) | NPC1HSP90AA1SLC6A2PLGPLAU | |
| SCHEMBL27083759 | 0.81 | GLS (0.58) | SMN1; SMN2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL29377015 | 0.81 | GLS (0.58) | SMN1; SMN2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL4201077 | 0.80 | PLG (0.44) | NPC1HSP90AA1SLC6A2PAX8PLG | |
| SCHEMBL4194376 | 0.79 | IDO1 (0.54) | NPC1HSP90AA1SLC29A1PAX8PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151487-A2 | SMALL-MOLECULE INHIBITORS OF ADAR1 | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-07-17 | — | — | WO | disclosed |