Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30146944 | 0.85 | DAO (0.55) | DAOALOX15ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7048502 | 0.85 | DAO (0.55) | DAOALOX15ALDH1A1HPGDHSD17B10 | |
| Phenol SCHEMBL10954832 | 0.74 | CYP2A6 (0.74) | ALOX15MEN1KMT2AKDM4EMAPT | |
| SCHEMBL17022664 | 0.74 | DAO (0.61) | DAOALOX15ALDH1A1CYP3A4HPGD | |
| SCHEMBL28280447 | 0.73 | FGFR1 (0.49) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10413632 | 0.71 | KMT2A (0.74) | DAOMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL980499 | 0.71 | AOC3 (0.54) | DAOMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30041175 | 0.71 | AOC3 (0.54) | DAOMEN1KMT2AKDM4EALDH1A1 | |
| 1,4-Dichlorobenzene SCHEMBL4557393 | 0.70 | CA12 (0.69) | ALOX15MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL7489718 | 0.69 | DAO (0.51) | DAOALOX15ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369657-A2 | Chromogenic substrate for esterase and immunoassay using same | Becton, Dickinson and Company (US) | 1990-05-23 | — | — | EP | claimed |
| CN-108477439-A | Vegetable beverage of broccoli containing selenium and preparation method thereof | 恩施土家族苗族自治州农业科学院 | 2018-09-04 | — | — | CN | disclosed |
| CN-107708440-A | Fructus Monordicae extract without agricultural chemicals and preparation method thereof | 莎罗雅株式会社 | 2018-02-16 | — | — | CN | disclosed |
| CN-106770241-B | Detect test paper component of Vitamin C content and preparation method thereof in liquid food | 张育宁 | 2018-02-06 | — | — | CN | disclosed |
| CN-103403174-B | Enzymatic synthesis of active pharmaceutical ingredients and intermediates thereof | 力奇制药公司 | 2017-10-27 | — | — | CN | disclosed |
| CN-106770241-A | Test paper component of Vitamin C content and preparation method thereof in detection liquid food | 张育宁 | 2017-05-31 | — | — | CN | disclosed |
| CN-103913440-A | Detection method and reagent of enzyme activity of pyruvate dehydrogenase complex | BEIJING HEXIN FEIFAN BIOTECHNOLOGY CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-103403174-A | Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof | LEK PHARMACEUTICALS | 2013-11-20 | — | — | CN | disclosed |
| US-8278451-B2 | Pseudoazulenyl nitrones | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100016349-A1 | PSEUDOAZULENYL NITRONES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2010-01-21 | — | — | US | disclosed |
| CN-101017134-A | Spectrophotometry for testing activity of pyruvic acid dehydrogenase system | UNIV HUAZHONG NORMAL (CN) | 2007-08-15 | — | — | CN | disclosed |
| EP-0888290-B1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNAT UNIVERSITY (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-0888290-A4 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNAT UNIVERSITY (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6291702-B1 | AS AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. | FLORIDA INTERNATIONAL UNIVERSITY | 2001-09-18 | — | — | US | disclosed |
| US-6197825-B1 | EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICAL SPECIES AND FIND USE AS EFFICIENT ANTIOXIDANTS IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS. DIAMAGNETIC NITRONE COMPOUND (THE ?SPIN TRAP?) REACTS WITH A TRANSIENT FREE | FLORIDA INTERNATIONAL UNIVERSITY | 2001-03-06 | — | — | US | disclosed |
| US-6083988-A | AZULENYL NITRONES ARE EFFECTIVE AGENTS FOR TRAPPING AND IDENTIFYING FREE RADICALS AND FIND USE AS EFFICIENT ANTIOXIDANT IN PHYSICOCHEMICAL AND BIOLOGICAL SYSTEMS | FLORIDA INTERNATIONAL UNIVERSITY | 2000-07-04 | — | — | US | disclosed |
| EP-0888290-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | Florida International University (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997019054-A9 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | — | 1997-08-07 | — | — | WO | disclosed |
| WO-1997019054-A1 | AZULENYL NITRONE SPIN TRAPPING AGENTS, METHODS OF MAKING AND USING SAME | FLORIDA INTERNATIONAL UNIVERSITY (US) | 1997-05-29 | — | — | WO | disclosed |
| EP-0286434-A2 | Method for the detection of bacteria and fungi | CAMBRIDGE BIOSCIENCE CORPORATION (US) | 1988-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016349-A1 | PSEUDOAZULENYL NITRONES | TXN2, NOX5, TXNRD2 | DAO 1259/4885ALOX15 268/4885MEN1 3491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.