SCHEMBL10413632

SCHEMBL10413632

Clc1ccc2cc(-c3ccccc3)[nH]c2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.74
ALDH1A1 P00352 5/20 0.74
MEN1 O00255 5/20 0.74
KDM4E B2RXH2 5/20 0.74
NPC1 O15118 4/20 0.74
RAB9A P51151 4/20 0.74
MAPT P10636 4/20 0.74
CYP19A1 P11511 4/20 0.74
LMNA P02545 2/20 0.74
SMN1; SMN2 Q16637 1/20 0.74
HPGD P15428 3/20 0.66
CASP3 P42574 2/20 0.66
SENP8 Q96LD8 2/20 0.66
SENP7 Q9BQF6 2/20 0.66
SENP6 Q9GZR1 2/20 0.66
CYP1A2 P05177 1/20 0.66
CYP2C9 P11712 1/20 0.66
CYP2C19 P33261 1/20 0.66
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27954031 0.93 KMT2A (0.66) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL27944100 0.88 ALDH1A1 (0.59) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL6117859 0.85 MEN1 (1.00) KMT2AALDH1A1MEN1KDM4ENPC1
Trifluoromethanesulfonic Acid SCHEMBL27954030 0.84 ALDH1A1 (0.55) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL695284 0.82 ALDH1A1 (0.57) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL12124985 0.82 NPC1 (0.75) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL5130538 0.81 NPC1 (0.68) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL1605273 0.80 CYP19A1 (0.68) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL11525006 0.80 ALDH1A1 (0.50) KMT2AALDH1A1MEN1KDM4ENPC1
SCHEMBL29941385 0.80 PLAU (0.62) KMT2AALDH1A1MEN1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same DOOSAN CORPORATION (KR) 2018-07-31 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-9837618-B2 Compound and organic electroluminescence device including thesame DOOSAN CORPORATION (KR) 2017-12-05 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
WO-2015111942-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2015-07-30 WO disclosed
CN-104736541-A Novel compound and organic electroluminescent element comprising same DOOSAN CORP 2015-06-24 CN disclosed
US-20140374724-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME DOOSAN CORPORATION (KR) 2014-12-25 US disclosed
WO-2014065498-A1 ORGANIC ELECTROLUMINESCENT DEVICE 주식회사 두산 (KR) 2014-05-01 WO disclosed
US-4403791-A Carbonless duplicating and marking systems STERLING DRUG INC. (US) 1983-09-13 US disclosed
US-4377698-A 2,4 Bis(2-indolyl-3)-4-oxobutanoic acids STERLING DRUG INC. (US) 1983-03-22 US disclosed
US-4351768-A CARBONLESS, DUPLICATION, INDOLE DYES STERLING DRUG INC. (US) 1982-09-28 US disclosed
US-4322352-A Indolyl phthalide compounds STERLING DRUG INC. (US) 1982-03-30 US disclosed
US-4307018-A CHROMOGENS FOR COPYING SYSTEMS STERLING DRUG INC. (US) 1981-12-22 US disclosed
US-4275121-A Carbonless duplicating and marking systems utilizing indolyl-substituted furanone color formers STERLING DRUG INC. (US) 1981-06-23 US disclosed
US-4257954-A INDOLYL-PHENYLSULFONYL-PHENYL METHANE STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4251446-A COLOR PRECURSORS STERLING DRUG INC. (US) 1981-02-17 US disclosed
US-4189171-A PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS STERLING DRUG INC. (US) 1980-02-19 US disclosed
US-4075224-A 3,5-Bis (indolyl)-5-(indolyl)-2(5H)-furanones STERLING DRUG INC. (US) 1978-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038146-B2 Organic light-emitting compound and organic electroluminescent device using same IDO1, IDO2, KYNU KMT2A 2669/4885ALDH1A1 458/4885MEN1 2218/4885
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 KMT2A 1344/4885ALDH1A1 1188/4885MEN1 2423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.