Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655283 | 1.00 | POLB (0.56) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL13593325 | 0.98 | POLB (0.55) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL13593333 | 0.98 | POLB (0.55) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL31661769 | 0.88 | POLB (0.69) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL7718043 | 0.88 | POLB (0.69) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL7717051 | 0.88 | POLB (0.69) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL5656576 | 0.88 | POLB (0.69) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL3046406 | 0.88 | POLB (0.69) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL7719057 | 0.86 | POLB (0.71) | POLBALDH1A1TDP1GAAALOX15 | |
| SCHEMBL7719074 | 0.82 | GAA (0.76) | POLBTDP1GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |