Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656576 | 1.00 | POLB (0.69) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL7717051 | 1.00 | POLB (0.69) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL31661769 | 1.00 | POLB (0.69) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL7718043 | 1.00 | POLB (0.69) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL7719057 | 0.95 | POLB (0.71) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL13593325 | 0.90 | POLB (0.55) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL13593333 | 0.90 | POLB (0.55) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL13166882 | 0.89 | POLB (0.76) | POLBALOX15MAPK1GAATDP1 | |
| SCHEMBL31661644 | 0.88 | POLB (0.56) | POLBALOX15MAPK1GAAALDH1A1 | |
| SCHEMBL5655283 | 0.88 | POLB (0.56) | POLBALOX15MAPK1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7186414-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1676832-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-6991798-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| US-6384278-B1 | REACTING AN AROMATIC AMINE AND AN ALKANOIC ACID OR ESTER IN THE PRESENCE OF A BORON COMPOUND AND OPTIONALLY, A CHELATING AGENT TO PRODUCE AN AROMATIC CARBOXAMIDE SUCH AS 8(5-CHLORO-2 -HYDROXYANILINO)-8-OXOOCTANOIC ACID | EMISPHERE TECHNOLOGIES, INC. | 2002-05-07 | — | — | US | disclosed |
| EP-1102742-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007979-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | POLB 985/4885ALOX15 818/4885MAPK1 4522/4885 |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | POLB 985/4885ALOX15 818/4885MAPK1 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.