Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661757 | 0.93 | HTR3A (0.40) | PLATS1PR1HTR3AHTR1AHTR7 | |
| SCHEMBL31661794 | 0.89 | S1PR1 (0.41) | S1PR1HTR3AHTR1AHTR1DHTR3E | |
| SCHEMBL31661584 | 0.84 | NR1H4 (0.37) | PLATS1PR1NR1H4KDM4EALDH1A1 | |
| SCHEMBL31661564 | 0.82 | MEN1 (0.44) | S1PR1NR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL31661551 | 0.82 | NPC1 (0.44) | S1PR1NR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL31661583 | 0.81 | S1PR1 (0.47) | S1PR1NR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL31661611 | 0.79 | NPC1 (0.41) | S1PR1NR1H4KDM4EALDH1A1HPGD | |
| SCHEMBL31661688 | 0.77 | SMN1; SMN2 (0.39) | PLATS1PR1NR1H4KDM4EALDH1A1 | |
| SCHEMBL31661825 | 0.77 | SMN1; SMN2 (0.39) | PLATS1PR1NR1H4KDM4EALDH1A1 | |
| SCHEMBL31661554 | 0.77 | SMN1; SMN2 (0.40) | S1PR1NR1H4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |