Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | USP1 | O94782 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661564 | 0.92 | MEN1 (0.44) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661757 | 0.88 | HTR3A (0.40) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661611 | 0.86 | NPC1 (0.41) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661554 | 0.86 | SMN1; SMN2 (0.40) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661825 | 0.85 | SMN1; SMN2 (0.39) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661688 | 0.85 | SMN1; SMN2 (0.39) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661780 | 0.84 | NPC1 (0.52) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661794 | 0.83 | S1PR1 (0.41) | S1PR1KDM4ETDP1SMN1; SMN2TP53 | |
| SCHEMBL31661671 | 0.82 | S1PR1 (0.47) | S1PR1KDM4ETDP1SMN1; SMN2USP1 | |
| SCHEMBL31661494 | 0.81 | USP1 (0.42) | S1PR1SMN1; SMN2TP53NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |