Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166172 | 0.95 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL7866274 | 0.93 | ELANE (0.58) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL30877912 | 0.92 | ELANE (0.57) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL10778406 | 0.88 | KMT2A (0.81) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL3168823 | 0.88 | ELANE (0.64) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL7857913 | 0.86 | ELANE (0.53) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL21879668 | 0.85 | ELANE (0.54) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL30877918 | 0.85 | POLB (0.69) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL30877928 | 0.84 | KMT2A (0.74) | SMN1; SMN2KMT2AHTTTDP1ELANE | |
| SCHEMBL9232274 | 0.84 | KMT2A (0.74) | SMN1; SMN2KMT2AHTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300459-B1 | TRANSESTERIFYING AROMATIC POLYCARBONATE AND ACTIVE-HYDROGEN COMPOUND UNDER REDUCED PRESSURE FOLLOWED BY REACTION WITH SPECIFIED SALICYLIC ESTER DERIVATIVE | TEIJIN LIMITED (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0982340-A1 | PROCESS FOR PRODUCING AROMATIC POLYCARBONATE | TEIJIN LIMITED (JP) | 2000-03-01 | — | — | EP | disclosed |