⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28722729 | 0.98 | SPHK2 (0.38) | — | |
| SCHEMBL4280721 | 0.93 | SPHK1 (0.43) | — | |
| SCHEMBL10006883 | 0.91 | SPHK1 (0.46) | — | |
| Iodide SCHEMBL5325544 | 0.91 | SPHK1 (0.41) | — | |
| SCHEMBL5848841 | 0.91 | SPHK1 (0.46) | — | |
| SCHEMBL4199885 | 0.85 | — | — | |
| SCHEMBL28846865 | 0.83 | SPHK2 (0.34) | — | |
| Acetic Acid SCHEMBL5849280 | 0.82 | HDAC3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL28575898 | 0.80 | FAAH (0.47) | — | |
| Octanoic Acid SCHEMBL5848069 | 0.78 | GPR84 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110087642-B | Prevention and treatment of migraine | 贝德尔巴塞尔大学儿童医院 | 2022-12-27 | — | — | CN | claimed |
| CN-115491367-A | Arginine decarboxylase mutant and application thereof in preparing guanidyl butylamine salt through immobilization | 武汉远大弘元股份有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-114624343-B | Method for relatively quantifying 45 inflammations and immune metabolites in serum | 中国科学院大连化学物理研究所 | 2023-01-24 | — | — | CN | disclosed |
| CN-115504909-A | Benzoylguanidine derivative and preparation method and application thereof | 青岛海洋生物医药研究院 | 2022-12-23 | — | — | CN | disclosed |
| CN-115491367-A | Arginine decarboxylase mutant and application thereof in preparing guanidyl butylamine salt through immobilization | 武汉远大弘元股份有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-113811293-A | Ketone bodies encapsulated in microbeads | 瑞士凯托股份公司 | 2021-12-17 | — | — | CN | disclosed |
| EP-3156394-B1 | ALKYLIDENE AMINOGANIDINE AND SALT THEREOF, MODIFIER COMPOSITION, MODIFIED RUBBER FOR TIRE, RUBBER COMPOSITION FOR TIRE, AND TIRE | MITSUBISHI GAS CHEMICAL CO (JP) | 2019-04-17 | — | — | EP | disclosed |
| US-9023417-B2 | Use of a polyamine-poor composition for the production of a medical human food | Univeriste de Rennes 1 (FR) | 2015-05-05 | — | — | US | disclosed |
| US-8778911-B2 | Use of a polyamine-depleted food composition for human or veterinary use, for preparing a therapeutic food product | UNIVERSITE DE RENNES 1 (FR) | 2014-07-15 | — | — | US | disclosed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8268871-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-09-18 | — | — | US | disclosed |
| WO-2005020974-A1 | NOVEL USE OF A POLYAMINE-POOR COMPOSITION FOR THE PRODUCTION OF A MEDICAL HUMAN FOOD | UNIVERSITE DE RENNES 1 (FR) | 2005-03-10 | — | — | WO | disclosed |
| US-20050003558-A1 | Biological sample component purification and differential display | CHIRON CORPORATION (US) | 2005-01-06 | — | — | US | disclosed |
| US-6783929-B1 | COMPRISES POLYAMIDE LIGANDS FOR ENHANCED EFFICIENCY OF PROTEOMICS | CHIRON CORPORATION | 2004-08-31 | — | — | US | disclosed |
| CN-1475210-A | New use of agmatine | 中国人民解放军军事医学科学院毒物药 | 2004-02-18 | — | — | CN | disclosed |
| WO-2003092668-A1 | USE OF AGMATINE FOR TOPICAL APPLICATION | WOHLRAB JOHANNES (DE) | 2003-11-13 | — | — | WO | disclosed |
| CN-1444930-A | New usage of agmatine | INST OF TOXICANT MEDICAMENT AC (CN) | 2003-10-01 | — | — | CN | disclosed |
| EP-1155327-A1 | BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY | CHIRON CORPORATION (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2001033230-A2 | BIOLOGICAL SAMPLE COMPONENT PURIFICATION AND DIFFERENTIAL DISPLAY | CHIRON CORPORATION (US) | 2001-05-10 | — | — | WO | disclosed |
| EP-0277626-A2 | Synthetic GHRH analogs | The Administrators of The Tulane Educational Fund (US) | 1988-08-10 | — | — | EP | disclosed |