Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.42 |
| ▸ | USP1 | O94782 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661817 | 1.00 | SCN9A (0.46) | SCN9APTGS2PTGS1USP1AR | |
| SCHEMBL30790422 | 0.88 | CYP11B2 (0.47) | SCN9APTGS2USP1EGLN2CYP11B1 | |
| SCHEMBL25975389 | 0.88 | CYP11B2 (0.47) | SCN9APTGS2USP1EGLN2CYP11B1 | |
| SCHEMBL31537604 | 0.85 | SCN9A (0.48) | SCN9APTGS2PTGS1USP1AR | |
| SCHEMBL31661801 | 0.85 | SCN9A (0.46) | SCN9APTGS2PTGS1USP1AR | |
| SCHEMBL25975390 | 0.85 | SCN9A (0.48) | SCN9APTGS2PTGS1USP1AR | |
| SCHEMBL18865809 | 0.80 | CYP11B2 (0.47) | SCN9APTGS2PTGS1USP1CYP11B2 | |
| SCHEMBL29864537 | 0.76 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL29863855 | 0.76 | PTGS2 (0.42) | PTGS2PTGS1USP1 | |
| SCHEMBL29863927 | 0.76 | PTGS2 (0.42) | PTGS2PTGS1USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |