Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.58 |
| ▸ | FEN1 | P39748 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081080 | 1.00 | ERCC5 (0.58) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL30808872 | 0.98 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL27636539 | 0.98 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL15619155 | 0.98 | ERCC5 (0.57) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL31661713 | 0.89 | ERCC5 (0.62) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL5081092 | 0.89 | ERCC5 (0.62) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL8573471 | 0.86 | ERCC5 (0.54) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL17746129 | 0.85 | ERCC5 (0.53) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL11747784 | 0.84 | ERCC5 (0.56) | ERCC5FEN1ALDH1A1TP53LMNA | |
| SCHEMBL13346899 | 0.84 | ALDH1A1 (0.62) | ERCC5FEN1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |