Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | ACKR3 | P25106 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527017 | 1.00 | CES2 (0.57) | CES2CES1ACKR3KMT2AMEN1 | |
| SCHEMBL5084694 | 0.85 | CES2 (0.57) | CES2CES1ACKR3KMT2AMEN1 | |
| SCHEMBL11582932 | 0.84 | HTT (0.49) | CES2CES1ACKR3KMT2AMEN1 | |
| SCHEMBL4707612 | 0.83 | CES2 (0.59) | CES2CES1ACKR3KDM4EALDH1A1 | |
| SCHEMBL14053155 | 0.82 | KMT2A (0.70) | ACKR3KMT2AMEN1HTTKDM4E | |
| SCHEMBL4091424 | 0.82 | HTT (0.62) | CES2CES1ACKR3KMT2AMEN1 | |
| SCHEMBL29788741 | 0.82 | CES2 (0.53) | CES2CES1ACKR3HTTKDM4E | |
| SCHEMBL3892255 | 0.82 | CES2 (0.53) | CES2CES1ACKR3HTTKDM4E | |
| SCHEMBL22097313 | 0.82 | PKM (0.49) | CES2CES1ACKR3KMT2AMEN1 | |
| SCHEMBL20268270 | 0.82 | CES2 (0.53) | CES2CES1ACKR3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |