Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 11/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27927303 | 0.99 | MKNK1 (0.53) | MKNK1MKNK2SCN9ACFTRKDR | |
| SCHEMBL6018315 | 0.84 | BCAT2 (0.56) | PARP1KDM4E | |
| SCHEMBL34469496 | 0.80 | PARP1 (0.54) | MKNK1MKNK2SCN9APARP1KDM4E | |
| SCHEMBL17111537 | 0.78 | JAK2 (0.46) | SORT1PARP1KDM4E | |
| SCHEMBL5990332 | 0.78 | CYP11B1 (0.51) | SCN9AKDRCYP11B1CYP11B2 | |
| SCHEMBL4442762 | 0.78 | MKNK1 (0.66) | MKNK1MKNK2CFTRKDR | |
| SCHEMBL28141005 | 0.77 | IDH2 (0.54) | SCN9AKDRCYP11B1CYP11B2EGFR | |
| SCHEMBL15009839 | 0.77 | CYP11B1 (0.50) | SCN9AKDRCYP11B1CYP11B2EGFR | |
| SCHEMBL15989428 | 0.77 | CYP11B1 (0.53) | MKNK1MKNK2SCN9ACFTRKDR | |
| SCHEMBL27724987 | 0.77 | KIF11 (0.50) | CFTRPARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |