Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915802 | 1.00 | MAPK1 (0.55) | MAPK1EGLN1POLBALDH1A1KDM4E | |
| SCHEMBL31661686 | 0.89 | NAAA (0.57) | MAPK1POLBALDH1A1KDM4ENPC1 | |
| SCHEMBL2164508 | 0.89 | NAAA (0.57) | MAPK1POLBALDH1A1KDM4ENPC1 | |
| SCHEMBL5656378 | 0.86 | MAPK1 (0.58) | MAPK1POLBALDH1A1KDM4EALOX5 | |
| SCHEMBL11026787 | 0.86 | MAPK1 (0.58) | MAPK1POLBALDH1A1KDM4EALOX5 | |
| SCHEMBL13577934 | 0.84 | NAAA (0.64) | EGLN1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12434386 | 0.84 | POLB (0.63) | MAPK1POLBALDH1A1NPC1RAB9A | |
| SCHEMBL5654581 | 0.83 | MAPK1 (0.55) | MAPK1POLBALDH1A1KDM4EALOX5 | |
| SCHEMBL4624092 | 0.83 | MAPK1 (0.55) | MAPK1POLBALDH1A1KDM4EALOX5 | |
| SCHEMBL16545132 | 0.83 | MAPK1 (0.55) | MAPK1POLBALDH1A1KDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151884-A1 | USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE | PARSONS C LOWELL (US) | 2025-07-17 | — | — | WO | disclosed |